Strategies for increasing innovation in big pharmaceutical companies

  • ŠPELA BARBIČ University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
  • LEA KNEZ Ludwig Maximilians University Munich, Germany.
  • ŠPELA KNEZ University of Ljubljana, Faculty of Biotechnology, Department of Genetics, Animal Biotechnology and Immunology, Slovenia. https://orcid.org/0000-0002-3538-2307
  • TJAŠA MLAKAR University of Ljubljana, Faculty of Chemistry and Chemical Technology, Chair of Biochemistry, Ljubljana, Slovenia.
  • SARA UHAN Charité - Universitätsmedizin Berlin, Department of Haematology, Oncology and Cancer Immunology, Germany. https://orcid.org/0000-0003-4102-5063
  • UROŠ VEZONIK University of Vienna, Institute of Organic Chemistry, Vienna, Austria. https://orcid.org/0000-0003-3991-5323
  • ZDENKO ČASAR University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia. https://orcid.org/0000-0002-6689-3353
Keywords: pharmaceutical companies, innovation, efficiency, research and development, SARS-CoV-2

Abstract

The overall technological, scientific and managerial progress of the last few decades is expected to be reflected in increased innovation and research efficiency in many entities, including large pharmaceutical companies. However, often the opposite can be observed. The efficiency of research and development (R&D), which can also be described as the input-output ratio, usually estimated by the number inhouse developed and launched medicines on the market or published scientific publications and granted patents, has been steadily declining in recent decades in the pharmaceutical industry. Nevertheless, especially in recent years many companies have shown successful resistance to this trend with an obvious increase in innovation, which among other things can be attributed to the improved financial efficiency and the design of new R&D models.

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Author Biographies

ŠPELA BARBIČ, University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

ŠPELA BARBIČ

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

E-mail: spelabarbi@gmail.com

LEA KNEZ, Ludwig Maximilians University Munich, Germany.

LEA KNEZ

Ludwig Maximilians University Munich, Germany.

E-mail: lea.knez07@gmail.com

ŠPELA KNEZ, University of Ljubljana, Faculty of Biotechnology, Department of Genetics, Animal Biotechnology and Immunology, Slovenia.

ŠPELA KNEZ

University of Ljubljana, Faculty of Biotechnology, Department of Genetics, Animal Biotechnology and Immunology, Slovenia.

E-mail: spela.knez@gmail.com

TJAŠA MLAKAR, University of Ljubljana, Faculty of Chemistry and Chemical Technology, Chair of Biochemistry, Ljubljana, Slovenia.

TJAŠA MLAKAR

University of Ljubljana, Faculty of Chemistry and Chemical Technology, Chair of Biochemistry, Ljubljana, Slovenia.

E-mail: tjasamlakar.15@gmail.com

SARA UHAN, Charité - Universitätsmedizin Berlin, Department of Haematology, Oncology and Cancer Immunology, Germany.

SARA UHAN

Charité - Universitätsmedizin Berlin, Department of Haematology, Oncology and Cancer Immunology, Germany.

E-mail: sara.uhan@charite.de

UROŠ VEZONIK, University of Vienna, Institute of Organic Chemistry, Vienna, Austria.

UROŠ VEZONIK

University of Vienna, Institute of Organic Chemistry, Vienna, Austria.

E-mail: uros.vezonik@univie.ac.at

ZDENKO ČASAR, University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

ZDENKO ČASAR

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

E-mail: zdenko.casar@ffa.uni-lj.si

Published
2023-10-26
How to Cite
BARBIČ ŠPELA, KNEZ L., KNEZ ŠPELA, MLAKAR T., UHAN S., VEZONIK U., & ČASAR Z. (2023). Strategies for increasing innovation in big pharmaceutical companies. Anali PAZU HD, 9(1-2), 95-123. https://doi.org/10.18690/analipazuhd.9.1-2.95-123.2023