Acute pancreatitis in a patient with normal lipase: a case report

Akutni pankreatitis z normalnimi vrednostmi lipaze: prikaz primera

  • Tjaša Kitanovski General Hospital Novo mesto, Emergency center; University medical centre Ljubljana, Institute of Radiology
  • Andrej Grahek General Hospital Novo mesto, Emergency center
  • Žan Garvas niversity of Ljubljana, Medical faculty
Keywords: pancreatitis, negative lipase, alcoholism, necrotizing pancreatitis, supportive care

Abstract

This case report highlights the rare occurrence of acute pancreatitis in a patient exhibiting normal lipase levels. The patient presented to the emergency department with abdominal pain and fever. Laboratory tests indicated an acute inflammatory process but a negative lipase value. The diagnosis was established by a CT scan showing necrotizing pancreatic changes with elevated carbohydrate-deficient transferrin (CDT) levels, suggesting alcohol as the etiology. Management involved supportive care, aggressive fluid resuscitation, nutritional support, and empirical antibiotic therapy, which led to clinical improvement. This case emphasizes the importance of a comprehensive clinical assessment beyond standard biochemical markers in diagnosing and managing pancreatitis.

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Author Biographies

Tjaša Kitanovski, General Hospital Novo mesto, Emergency center; University medical centre Ljubljana, Institute of Radiology

Slovenia.

Andrej Grahek, General Hospital Novo mesto, Emergency center

Novo mesto, Slovenia.

Žan Garvas, niversity of Ljubljana, Medical faculty

Ljubljana, Slovenia.

Published
2024-07-12
How to Cite
Kitanovski T., Grahek A., & Garvas Žan. (2024). Acute pancreatitis in a patient with normal lipase: a case report. Acta Medico-Biotechnica, 17(1), 52-56. https://doi.org/10.18690/actabiomed.268
Section
Articles