Polyneuritis cranialis related to SARS-CoV-2 infection: a case report

Kranialni polinevritis, povezan z okužbo s SARS-CoV-2: prikaz primera

  • Peter Gradišnik University Medical Center Maribor, Department of Pediatrics
  • Andreja Osterc Koprivšek University Medical Center Maribor, Department of Pediatrics
  • Miha Rus University Clinical Center Maribor, Pediatric Intensive Care Unit
  • Tanja Golli University Medical Centre Ljubljana, University Children's Hospital, Department of Pediatric Neurology
  • Hermina Damjan University Rehabilitation Institute
DOI: https://doi.org/10.18690/actabiomed.251
Keywords: Polyneuritis cranialis, Miller Fisher syndrome, Multiple cranial nerve palsy, Coronavirus disease

Abstract

Purpose: Polyneuritis cranialis (PNC) is a less known regional variant of Guillain-Barré syndrome and has rarely been described in children. Here, we report a case of an adolescent, who became perilously ill following severe acute respiratory syndrome-coronavirus 2 infection.

Case report: A 15-year-old boy presented with acute multiple cranial nerve palsies. The presence of GQ1b antibodies and nerve conduction studies confirmed the diagnosis of PNC. The patient was treated with plasmapheresis and intravenous immunoglobulins, but clinical improvement was gradual and very slow.

Conclusion: PNC is a rare and severe neurologic condition that can be triggered by coronavirus infection.

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Author Biographies

Peter Gradišnik, University Medical Center Maribor, Department of Pediatrics

Maribor, Slovenia.

Andreja Osterc Koprivšek, University Medical Center Maribor, Department of Pediatrics

Maribor, Slovenia.

Miha Rus, University Clinical Center Maribor, Pediatric Intensive Care Unit

Maribor, Slovenia.

Tanja Golli, University Medical Centre Ljubljana, University Children's Hospital, Department of Pediatric Neurology

Ljubljana, Slovenia.

Hermina Damjan, University Rehabilitation Institute

Ljubljana, Slovenia.

Published
2023-07-12
How to Cite
Gradišnik P., Osterc Koprivšek A., Rus M., Golli T., & Damjan H. (2023). Polyneuritis cranialis related to SARS-CoV-2 infection: a case report. Acta Medico-Biotechnica, 16(1), 53-56. https://doi.org/10.18690/actabiomed.251
Issue
Vol 16 No 1 (2023)
Section
Articles

Copyright (c) 2023 Peter Gradišnik, Andreja Osterc Koprivšek, Miha Rus, Tanja Golli, Hermina Damjan (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.