How and why to analyze microbiota – a quick guide for clinicians

Kako in zakaj analiziramo mikrobioto – hitri vodnik za zdravnik

Authors

  • Sabina Horvat University of Maribor, Faculty of Medicine Author
  • Maja Rupnik University of Maribor, Faculty of Medicine; National laboratory for health, environment and food (NLZOH), Center for medical microbiology, Department for microbiological research Author

DOI:

https://doi.org/10.18690/actabiomed.191

Keywords:

microbiota, metagenomics, next generation sequencing, personalized medicine, disease markers

Abstract

Microbiota is defined as a microbial population inhabiting a given body part. The best known example is the gut microbiota, but oral, vaginal, and skin microbiota have also been studied extensively. Many body parts previously thought to be sterile have been shown to possess their own specific microbiota. Each microbiota plays an important role in organ functioning, in health, or in disease development. Therefore, microbiotas are widely studied in an effort to establish possible health or disease markers, or to use microbiota as potential therapeutic targets. The literature on microbiota has increased exponentially along with the development of methods used for analysis. An understanding of the basic principles and terms used in microbiota studies are therefore an important part of a clinician’s education.

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Author Biographies

  • Sabina Horvat, University of Maribor, Faculty of Medicine

    Maribor, Slovenia.

  • Maja Rupnik, University of Maribor, Faculty of Medicine; National laboratory for health, environment and food (NLZOH), Center for medical microbiology, Department for microbiological research

    Prof., Maribor, Slovenia. E-mail: maja.rupnik@nlzoh.si

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Published

29.11.2021

Issue

Section

Articles

How to Cite

Horvat, S., & Rupnik, M. . (2021). How and why to analyze microbiota – a quick guide for clinicians: Kako in zakaj analiziramo mikrobioto – hitri vodnik za zdravnik. Acta Medico-Biotechnica, 13(1), 11-22. https://doi.org/10.18690/actabiomed.191